Researchers examine benefits of hyperbaric oxygen in treatment of ...

In a singular study, researchers during The Long Island Brain Tumor Center during Neurological Surgery, P.C. are examining either hyperbaric oxygen therapy ? respirating pristine oxygen while in a pressurized cover ? might infer a useful further to a stream customary of caring for patients newly diagnosed with glioblastoma, an assertive mind cancer. The Phase II investigate is now enrolling participants, and is being conducted during Neurological Surgery, P.C. offices in Nassau and Suffolk Counties, New York, as good as during Winthrop University Hospital, Mineola, NY.

?Malignant glioblastoma is a many assertive form of mind cancer, and it generally has a bad prognosis,? says neuro-oncologist J. Paul Duic, MD, principal questioner on a investigate and co-director of The Long Island Brain Tumor Center. ?Novel diagnosis strategies are clearly needed.?

Malignant mind tumors are a second heading means of cancer deaths in people underneath 35, and a fourth heading means of cancer genocide in people underneath 54. Glioblastoma is a many common and many assertive primary (non-metastatic) form of mind cancer. Median presence for glioblastomas is 12-14 months, and usually 26 percent of patients tarry dual years.

Patients enrolled in a investigate contingency be newly diagnosed with virulent glioblastoma, and have formerly perceived mind growth surgery, though not deviation or chemotherapy. All patients in a investigate will accept a stream customary of caring for those newly diagnosed with glioblastoma ? temozolomide (Temodar?) and deviation therapy ? as good as hyperbaric oxygen therapy.

?We know that these mind tumors cite a low-oxygen metabolic state, and there is justification that this metabolic state might minister to a tumors? ability to conflict a effects of deviation therapy and chemotherapy,? says Jai Grewal, MD, sub-investigator on a investigate and co-director of The Long Island Brain Tumor Center. ?We wish to see either augmenting a oxygen thoroughness of a growth increases a efficacy of customary therapy.?

Drs. Duic and Grewal are also meddlesome in evaluating a outcome of this treatment?on patients? peculiarity of life and highlight levels. Participants will be asked to finish several brief questionnaires.

Hyperbaric oxygen has shown some advantage in pre-clinical studies, and in dual new Japanese clinical trials. In a initial clinical trial, published in 2006, Ogawa and colleagues found that patients who perceived deviation therapy immediately after hyperbaric oxygenation, total with chemotherapy, had longer presence rates, comparatively few inauspicious events and no late toxicities. In 2007, Kohshi and colleagues reported additional presence advantages with minimal additional toxicity for formerly treated high-grade glioma patients who were given hyperbaric oxygen total with stereotactic radiosurgery.

Source: http://www.cubworldepk.com/researchers-examine-benefits-of-hyperbaric-oxygen-in-treatment-of-aggressive-brain-cancer.html

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