A robot with 200 hours of power? DARPA wants one

6 hrs.

John Roach

The U.S. military?s futuristic research arm has launched a program to get more productivity out of its robots in a bid to make them more compatible companions on the battlefield.

DARPA?s robots include one that can haul hundreds of pounds of gear across rugged terrain and another that can quickly disarm roadside bombs ? good chores for robots instead of humans. The problem is the machines are lazy, working for about 10 minutes before they demand a re-charge break.

The agency?s M3 Actuation program aims to achieve a 2,000 percent increase in the efficiency of power transmission and application in robots.

To get there, the agency suggests researchers look to human and animal models, whose bones, muscles and tendons have evolved to work together and use as little energy as possible.?

?If robotic actuation can be made to approach the efficiency of human and animal actuation, the range of practical robotic applications will greatly increase and robot design will be less limited by power plant considerations,? DARPA said in a statement announcing the program.

According to the statement, the agency is seeking proposals for two tracks:?

• Track 1 is to demonstrate develop and demonstrate high-efficiency actuation technology that will allow robots similar to the government-furnished ones in the DARPA Robotics Challenge to have a 20 times longer endurance when running on untethered battery power. (Currently about 10 to 20 minutes.)
  
• Track 2 aims to improve the efficiency of actuators at scales larger and smaller than applicable to the DRC GFE platform.
  

Design approaches will be shared at the DRC live competition scheduled for December 2013 and final systems will be demonstrated at DRC live in December 2014. More details are available from DARPA.?

John Roach is a contributing writer for msnbc.com. To learn more about him, check out his website and follow him on Twitter. For more of our Future of Technology series, watch the featured video below.

Source: http://www.futureoftech.msnbc.msn.com/technology/futureoftech/robot-200-hours-power-darpa-wants-one-860991

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Bailout envoy urges Greece to speed up reforms

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Source: http://news.yahoo.com/bailout-envoy-urges-greece-speed-reforms-075549668--finance.html

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IBM Labs pitches the future of augmented reality shopping with mobile app prototype

From the same company that brought you the ThinkPad and the tank of a keyboard known as the Model M, today IBM is demonstrating its latest consumer development: a mobile shopping app. As odd as that sounds, it's no secret that Big Blue employs some rather brilliant folk, and now the company is looking to combine augmented reality with your everyday shopping habits. While still merely a prototype, the app will allow consumers to pan product aisles with their smartphone camera and view additional details on the screen. As IBM puts it, shoppers may input their own needs and preferences into the app, which can accommodate a wealth of information such as allergens, sugar content and bio-degradable packaging. Through partnerships with retailers, IBM also hopes to integrate promotions and loyalty schemes into the app, which it states will help stores better understand the buying habits of individual consumers. So there you have it, the future of shopping, as brought to you by IBM. As for the full PR, you'll find it after the break.

Continue reading IBM Labs pitches the future of augmented reality shopping with mobile app prototype

IBM Labs pitches the future of augmented reality shopping with mobile app prototype originally appeared on Engadget on Mon, 02 Jul 2012 00:01:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/07/02/ibm-augmented-reality-shopping-app/

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'Miss Holocaust Survivor' crowned in Israel, stirring smiles and controversy

HAIFA, Israel - Fourteen women who survived the horrors of World War II paraded Thursday in an unusual pageant, vying for the honour of being crowned Israel's first "Miss Holocaust Survivor."

Billed by organizers as a celebration of life, the event also stirred controversy. In a country where millions have been touched by the Holocaust, many argued that judging aging women who had suffered so much on physical appearance was inappropriate, and even offensive.

"It sounds totally macabre to me," said Colette Avital, chairwoman of Israel's leading Holocaust survivors' umbrella group. "I am in favour of enriching lives, but a one-time pageant masquerading (survivors) with beautiful clothes is not what is going to make their lives more meaningful."

Pageant organizer Shimon Sabag rejected the criticism, saying the winners were chosen based on their personal stories of survival and rebuilding their lives after the war, and physical beauty was only a tiny part of the competition.

"They feel good together. They are having a good time and laughing in the rehearsals," said Sabag, director of Yad Ezer L'Haver, or Helping Hand, which assists needy Holocaust survivors and organized the pageant.

"The fact that so many wanted to participate proves that it's a good idea."

Nearly 300 women from across Israel registered for the competition and contestants were whittled down to the 14 finalists who appeared Thursday.

The contest, part of Helping Hand's annual "cultural" night, included a lavish dinner and music at a Haifa reception hall. Some 600 people attended, including two Cabinet ministers, Moshe Kahlon and Yossi Peled, himself a Holocaust survivor.

The women, ranging in age from 74 to 97, clearly enjoyed themselves. Wearing black dresses, earrings and necklaces, and sporting blue-and-white numbered sashes, they grinned and waved as they were introduced to the adoring audience. Music played as the contestants walked along a red carpet, introduced themselves and described their memories of World War II.

"I have the privilege to show the world that Hitler wanted to exterminate us and we are alive. We are also enjoying life. Thank God it's that way," said Esther Libber, a 74-year-old runner-up who fled her home in Poland as a child, hid in a forest and was rescued by a Polish woman. She said she lost her entire immediate family.

A four-judge panel consisting of three former beauty queens and a geriatric psychiatrist who specializes in treating Holocaust survivors chose the winner. Hava Hershkovitz, a soon-to-be 79-year-old, was banished from her home in Romania in 1941 and sent to a detention camp in the Soviet Union for three years. Today, she lives in an assisted living home run by Helping Hand.

"This place is full of survivors. It puts us at the centre of attention so people will care. It's not easy at this age to be in a beauty contest, but we're all doing it to show that we're still here," the silver-haired Hershkovitz said.

Wearing a glittering tiara, she was joined by her granddaughter, Keren Hazan. "I'm very proud of her because she's the most beautiful woman in the room tonight," Hazan said.

In addition to the contestants' accounts of surviving Nazi ghettos and concentration camps, their later contributions to their communities were also considered, Sabag said. Physical appearance was maybe "10 per cent" of the criteria, he said, though a cosmetics company was recruited to help the women dress up for the occasion.

"We always tell them to dress well and look good. To think positive and to take care of themselves," Sabag said. "Always look at life with a smile and continue to live."

The thought that physical appearance could even remotely be a factor rubbed some the wrong way. Avital, of the Holocaust survivors' umbrella group, criticized the cosmetics company, saying it was using Holocaust survivors in a cheap marketing stunt to promote their products.

"Why use a beauty contest to show that these people survived and that they're brave?" wondered Lili Haber, a daughter of Holocaust survivors who heads an Israeli organization that assists survivors from Poland. "I think it's awful. I think it's something a decent person shouldn't even think about."

The Holocaust, in which Nazi Germany oversaw the systematic slaughter of 6 million European Jews, plays a unique role in Israeli society. The country gained independence in the wake of the Holocaust, serving as a refuge for hundreds of thousands of people who survived the genocide.

Nearly 200,000 aging survivors live in Israel today, and the country's annual Holocaust Day is one of the most solemn occasions on the calendar. Restaurants and cinemas close, and the country comes to a standstill as sirens wail for two minutes. Israeli leaders, including Prime Minister Benjamin Netanyahu, frequently make references to the Holocaust when discussing the threat they believe a nuclear-armed Iran would pose to the Jewish state.

Thursday's contest was among the many unconventional beauty pageants that have sprouted up over the years. The war-torn countries of Angola and Cambodia have held "Miss Landmine" contests for survivors of land mine explosions, Star Trek fans enjoy the "Miss Klingon Empire" contest in Atlanta, and plus-sized women in Thailand compete for the honour of "Miss Jumbo Queen." There are also a senior citizens' pageants in the U.S.

Gal Mor, editor of the popular Israeli blog "Holes in the Net," said Thursday's pageant was well-intentioned but misguided.

"Why should a decayed, competitive institution that emphasizes women's appearance be used as inspiration, instead of allowing them to tell their story without gimmicks?" he wrote. "This is one step short of 'Survivor-Holocaust' or 'Big Brother Auschwitz.' It leaves a bad taste. Holocaust survivors should be above all this."

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Djokovic savors opening day honors on Centre Court

WIMBLEDON, England (AP) ? Being a defending champion at Wimbledon has its perks ? none bigger than the honor of playing the opening match on the freshly manicured lawn of Centre Court.

Despite slipping on the slick grass and falling behind early in the first set, Novak Djokovic quickly gained his footing and played the commanding tennis that took him to his first Wimbledon title and vaulted him to the No. 1 ranking that he still holds.

Last year, after beating Rafael Nadal in the final, Djokovic grabbed some blades of grass and stuffed them into his mouth. This time, he celebrated quietly after defeating another Spaniard, dropping just seven games in a 6-3, 6-3, 6-1 win Monday over former No. 1 Juan Carlos Ferrero.

"It's a very unique feeling," Djokovic said of stepping onto the sport's most famous stage at 1 p.m. as reigning champ. "I think that's the first time I experienced that in my career. I think this is the only tournament that actually allows you to have information when you're playing 12 months in advance."

Following his loss to Nadal in the French Open final two weeks ago that ended the Serb's 27-match winning streak at Grand Slams, Djokovic came to Wimbledon without any grass-court preparation. He got off to a shaky start and lost serve to fall behind 2-1, but broke right back and took complete command.

"The grass was untouched," he said. "It was soft, so smooth. It was great to play in."

The atmosphere, too, was special when he came onto the court.

"It is quieter than the other center courts of the other Grand Slams," Djokovic said. "But you feel that tradition and the history of tennis, of sport, in this tournament, especially Centre Court. So many legends have won the trophies here, the trophies that made them big tennis stars."

While Djokovic paid tribute to the tradition, he also pulled off a very untraditional bit of gimmickry: taking a golf club with him onto the court.

As part of an inside joke with a sponsor, he pulled a club out of his racket bag and put it on the sideline when he arrived to face Ferrero.

"It was a little funny thing," said Djokovic, whose racket maker gave him a bag that has posts to make it stand like a golf bag. "Being creative, that's all. But fans corrected me right away. They said, 'This is not a golf course.' I said, 'OK.'"

Djokovic has won four of the past six Grand Slam tournaments, breaking up what had been the two-man dominance of Nadal and Roger Federer. The three players have combined to win 28 of the past 29 major titles.

"There is not anymore advantages in ... my favor, Rafa's, Roger's, whenever we are playing each other on any surface," Djokovic said. "We're all kind of equal, in a way. I think we have equal, 50-50, chances to win."

Day 1 passed off without a single rain delay, a relief after one of the wettest Junes on record in Britain.

Other winners included six-time champion Federer, top-seeded Maria Sharapova, four-time Grand Slam champion Kim Clijsters and No. 3 Agnieszka Radwanska.

Five-time champion Venus Williams lost and won't be playing in the second round at Wimbledon for the first time since her debut at the All England Club in 1997.

The highest seeded player to fall was No. 6 Tomas Berdych, the 2010 runner-up who lost 7-6 (5) 7-6 (4) 7-6 (4) to 87th-ranked Ernests Gulbis of Latvia.

John Isner, the 11th-seeded American, squandered a match point in the fourth set and was upset in five by Alejandro Falla of Colombia, 6-4, 6-7 (7), 3-6, 7-6 (7), 7-5. The result ruled out a second-round contest between Isner and Nicolas Mahut ? who played the longest match in tennis history here two years ago, and met again in the first round last year.

While Djokovic did the Centre Court honors on Monday, it will be defending women's champ Petra Kvitova's turn on Tuesday, opening against Akgul Amanmuradova of Uzbekistan.

Second-seeded Nadal was scheduled up next against Thomaz Bellucci of Brazil, followed by No. 4 Andy Murray against former top-10 player Nikolay Davydenko. On Court 1, fifth-seeded Jo-Wilfried Tsonga was paired against 2002 champion Lleyton Hewitt, who has slipped to 202nd in the rankings and needed a wild card to enter Wimbledon this year.

A day after her sister was eliminated on Court 2, four-time champion and sixth-seeded Serena Williams was due to play on the same court against Barbora Zahlavova Strycova. Williams openly wondered last year why the sisters were put on Court 2 instead of Centre Court.

Venus Williams was eliminated 6-1, 6-3 by Elena Vesnina of Russia, the latest setback in her return to tennis after being diagnosed with Sjogren's syndrome, an autoimmune disease that can cause fatigue and joint pain.

Williams, who has fallen to 58th in the rankings, lost the first five games to the 79th-ranked Russian and, although she picked up her game and fought hard, was never able to turn the match around. Afterward, she insisted she still has the motivation to return to the top of her game.

"I feel like I'm a great player," Williams said. "I am a great player. Unfortunately I have to deal with circumstances that people don't have to deal with normally in a sport, but I can't be discouraged by that. I'm up for challenges. I have great tennis in me. I just need the opportunity."

The next chance will be the Olympic tournament, which will be played at Wimbledon three weeks after the end of the championships. Venus, who won gold in women's singles and doubles at the 2000 Olympics and bronze in doubles in Beijing four years ago, hopes to play both events again at the London Games.

"At the Olympics, you'll see me here," she said. "I'm planning on it."

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Molecule thought cancer foe actually helps thyroid tumors grow

ScienceDaily (June 20, 2012) ? A molecule widely believed to fight many forms of cancer actually helps deadly thyroid tumors grow, and cancer therapies now being tested in humans might boost the activity of this newly revealed bad guy, researchers at Mayo Clinic in Florida say.

Their findings are published online this month in the Journal of Cell Science.

The study found that in anaplastic thyroid cancer, the Forkhead transcription factor, FOXO3a, is not the helpful tumor suppressor everyone thought it was, but, instead, is a lethal promoter of tumor growth. When FOXO3a was silenced in laboratory models of human anaplastic thyroid cancer, the cells grew slowly, but when it was added, they grew much faster.

"This result is exactly the opposite of what we expected," says senior author John A. Copland, Ph.D., a Mayo cancer biologist. "We were more than surprised. We were concerned."

FOXO3a is known as a suppressor of tumor growth because it responds to all forms of cell stress, including that produced in cancer, by turning on genes inside the nucleus that trigger the cell's death. Cancer, in turn, is known to shut down FOXO3a by sending it out of the nucleus and into the cell's cytoplasm, where it is degraded. The molecule that ships FOXO3a out of the nucleus is Akt, which tries to keep cancer cells alive.

The research team used an Akt blocker -- similar to the ones now being used in human cancer clinical trials -- expecting to increase nuclear FOXO3a and suppress cancer growth in anaplastic thyroid cancer. They were trying to find a treatment for one of the deadliest known cancers, which accounts for just 2 percent of thyroid cancer cases in the U.S. but is responsible for about 40 percent of thyroid cancer deaths.

"The issue we are grappling with is that there are no effective treatments for this cancer. These tumors are so aggressive because there are so many genetic abnormalities," says study co-author Robert Smallridge, M.D., a Mayo endocrinologist who treats thyroid cancer patients. "We are studying what drives this cancer and how it can be treated."

The study showed that FOXO3a remained in the nucleus, with the use of an Akt inhibitor, and that instead of helping to kill cancer cells, FOXO3a was accelerating their growth. This raises concern about the use of Akt inhibitors since one of the mechanisms is to cause FOXO3a to remain active in the nucleus.

"We discovered a biological switch that turns FOXO3a from a good guy into a bad actor, but we don't know what that is yet, or in which cancers that might happen," says lead researcher Laura Marlow, a Mayo biologist.

"Cancer researchers, including those testing Akt inhibitors, should know that FOXO3a has pro-cancer activity as well as anti-cancer properties," Dr. Copland says. "Concern should be raised that an Akt inhibitor will enhance retention of FOXO3a in the nucleus, causing FOXO3a to remain active.

But there was some hopeful news regarding a potential therapy for the cancer. The researchers found that FOXO3a turns on a certain gene, cyclin A1, which promotes growth in the cancer cells. A different member of the cyclin family -- cyclin A2 -- is a well-known oncogene, but, before this study, no one had shown that cyclin A1 does the same thing as cyclin A2, says Peter Storz, Ph.D., a Mayo cancer biologist and co-author.

"It is not expressed much in human tissues and we found it highly expressed in anaplastic thyroid cancer," Dr. Smallridge says. "And that suggests that targeting cyclin A1 may be a possible strategy in treating anaplastic thyroid cancer."

The study was funded in part by the National Institutes of Health/National Cancer Institute, Mayo Clinic Research Committee, Florida Department of Health Bankhead-Coley Cancer Research Program, a gift from Alfred D. and Audrey M. Petersen, a grant for rare cancers from Dr. Ellis and Dona Brunton, and TGEN Institutional Research Funds. Co-authors included Christina von Roemeling, Simon Cooper, Ph.D., Yilin Zhang, Stephen Rohl, Han Tun, M.D., and Heike Doeppler, all from Mayo Clinic in Florida; Shilpi Arora, Ph.D., Irma M. Gonzales, Ph.D., and David O. Azorsa, Ph.D., all from The Translational Genomics Research Institute (TGen); and Honey V. Reddi, Ph.D., from Mayo Clinic in Rochester.

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Journal Reference:

1. Laura A. Marlow, Christina A. von Roemeling, Simon J. Cooper, Yilin Zhang, Stephen D. Rohl, Shilpi Arora, Irma M. Gonzales, David O. Azorsa, Honey V. Reddi, Han W. Tun, Heike R. D?ppler, Peter Storz, Robert C. Smallridge, and John A. Copland. Foxo3a drives proliferation in anaplastic thyroid carcinoma via transcriptional regulation of cyclin A1: A paradigm shift that impacts current therapeutic strategies. Journal of Cell Science, June 20, 2012 DOI: 10.1242/jcs.097428

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Teen Drinkers May Feel Like Social Outcasts: Study

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